Former president Jacob Zuma's son, Vusi Nhlakanipho Zuma, died as a result of lupus, a family representative said on Wednesday.
"[He] departed on the 1st July 2018 from complications of systematic lupus erythematosus, simply known as lupus," said family spokesperson Linda Makatini in a statement.
Lupus disease causes chronic inflammation as an autoimmune response to the body's own cells.
Health24: Lupus
The family said it would gather at home in Forest Town on Wednesday night for prayers to remember Vusi Zuma - who was the youngest son of Zuma and his late wife Kate Mantsho.
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A memorial service would be held on Thursday. This will only be open to close friends and family.
The funeral service would then take place on Saturday at 09:00 at the Rhema Recreational Centre in Randburg. Vusi Zuma will be buried at West Park Cemetery.