BioFlux is a microfluidic platform analysis system with the ability to simultaneously grow up to 96 biofilms under controlled shear conditions. The product features quick and easy set-up with no messy pumps or tubing.
Bacteria and fungi organised into biofilms are highly refractive to known antibiotics and biocides. To develop biofilm solutions, screening technologies must be designed to grow biofilms under conditions that represent an in vivo or in situ community, while maintaining the ability to add and observe the effects of compounds.
BioFlux offers a comprehensive solution for running both fundamental biology assays as well as antimicrobial compound screens. Representative applications include biofilm growth, mutant screens, antibacterial or antifungal screening, host-pathogen interactions and adhesion strength.
The system is proficient in controlled media flow for up to 21 days, reducing media consumption and the use of stains and drug compounds. With two-inlet designs, scientists can perform, for example, multiple parallel bacterial chemotaxis experiments and competitive biofilm development assays. With the ability to control temperature, gas content and nutrient delivery, users can even grow anaerobic biofilms, as the system controls shear forces to quantify bacterial adhesion.