Strategies to counter the ongoing global threat of multidrug-resistant organisms, including Clostridium difficile, are crucial to the future of medicine.1 The direct effect of enhanced terminal room disinfection was previously illustrated in the Benefits of Enhanced Terminal Room (BETR) Disinfection study,2 a prospective, multicentre, cluster-randomised, crossover study done in nine US hospitals with four strategies for terminal hospital room cleaning in targeted rooms. Strategies included a reference group for terminal disinfection with quaternary ammonium (quat), along with three enhanced strategies: bleach, quat with disinfecting ultraviolet light (UV-C), and bleach with UV-C.