Patients with ulcerative colitis who have a higher BMI are at an increased risk for failing biologic therapy, regardless of the dosing regimen, according to new research published in Alimentary Pharmacology & Therapeutics.
Obesity has long been associated with a higher risk for developing Crohn’s disease, but no such link has been observed for ulcerative colitis (UC). Siddarth Singh, MD, of the division of gastroenterology at the University of California San Diego, and colleagues sought to determine if obesity might affect these patients already seeking treatment for UC.
“We
Original Article: Obesity linked to biologics failure in UC