Amgen Inc. shares rose more than 1% late Tuesday after the company reported first-quarter sales and profit above Wall Street expectations and revised its guidance. Amgen said it earned $2.31 billion, or $3.25 a share, in the quarter, compared with $2.07 billion, or $2.79 a share, in the year-ago period. Adjusted for one-time items, Amgen earned $2.46 billion, or $3.47 a share, compared with $2.33 billion, or $3.15 a share, a year ago. Sales rose 2% to $5.55 billion, compared with $5.46 billion a year ago. Analysts polled by FactSet had expected adjusted earnings of $3.22 a share on sales of $5.43 billion. "Amgen's strong first-quarter performance was driven by our new and recently launched products, all of which delivered double-digit, volume-driven growth," Chief Executive Robert A. Bradway said in a statement. The company said it expects 2018 per-share GAAP earnings between $11.30 to $12.28, and sales between $21.9 billion and $22.8 billion. The analysts surveyed by FactSet expect 2018 GAAP per-share earnings around $13.48 on sales of $22.6 billion. The shares ended the regular session down 1.6%.