U.S. government debt prices fell into the red on Wednesday.
The yield on the benchmark 10-year Treasury note was higher at around 2.828 percent at 5:10 a.m. ET, while the yield on the 30-year Treasury bond was higher at 3.013 percent. Bond yields move inversely to prices.
On Wednesday, it's all about news coming from the U.S. central bank for bond investors, with speeches by members of the U.S. Federal Reserve expected to be in focus.
In New York, New York Fed President William Dudley is due to speak at two events: one at the Community Bankers Conference on navigating future risks for community banks, and another at Lehman College on the state of the economy.
Meantime, Fed Governor Randal Quarles will be in Washington DC, where he is due to appear at the Bretton Woods Committee 2018 annual meeting.
Sticking with the subject, the Fed's Beige Book is due to be released at 2 p.m. ET, which could provide investors with additional clues on how the U.S. economy is currently performing. Aside from this, mortgage applications are due out at 7 a.m. ET.
Elsewhere, President Donald Trump will be hosting the second day of an official working visit by Japanese Prime Minister Shinzo Abe in Florida, where the two leaders are expected to talk about peace and stability in the Indo-Pacific region, trade and investment ties.
No major auctions are scheduled to take place by the U.S. Treasury on Wednesday.