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In a largely uncontested attack, U.S., British and French forces unleashed 105 missiles on three Syrian chemical weapons facilities early Saturday, leveling at least one building and setting back the country's chemical weapons program "for years," Pentagon officials said.

The strikes targeted three areas of Syria: a scientific research center near Damascus, a chemical weapons storage facility west of Homs and a storage facility and command post near Homs.

Lt. Gen. Kenneth McKenzie, director of the Joint Staff at the Pentagon, told reporters Saturday that the weapons used in the operation were a mix of sea and air-launched missiles fired by U.S., British and French forces and “successfully hit every target.”

The goal, he said, was to hit the "very heart" of Syria's chemical weapons program by targeting its research, development and storage facilities. The strikes come one week after reports of a grisly chemical attack in the town of Douma that killed more than 40 people.   

"This is going to set the Syrian chemical weapons program back for years," McKenzie said.

Syrian forces fired 40 surface-to-air missiles during the operation, mostly after the attack was over, he said.

"They were largely ineffective and increased risk to their own people," he said. “None of our aircraft or missiles involved in this operation were successfully engaged by Syrian air defenses.”

He also said there was no indication that Russian air-defense systems were employed during the attacks.

McKenzie said there were no initial reports of civilian casualties in large part because the operation was planned to be carried out during the night. "We weren't trying to kill a lot of people," he said.

President Trump, in a Saturday morning tweet, called the nighttime attack a "perfectly executed strike." 

"Mission Accomplished!" he added.

Gen. Joseph Dunford, the chairman of the Joint Chiefs of Staff, said late Friday that that the operation was "a one-time shot” but did not rule out further attacks.

While the Pentagon stressed the narrow, precise-nature of the attacks, Trump emphasized in announcing the strikes that the allied forces "are prepared to sustain this response until the Syrian regime stops its use of prohibited chemical agents."

Syria has denied using chemical weapons. But Friday night, the White House released what it said was "a significant body of information" that pointed to the use of chlorine gas — and possibly also the deadly nerve agent sarin. That evidence includes victim statements, images of barrel bomb fragments and reliable reports of Syrian government helicopters in the area.

In addition, France issued a "national assessment" on the chemical attack based on intelligence reports, information from non-governmental sources, such as relief teams, on the scene and a close examination of information and video from social media. 

The report said France considers it "beyond possible doubt" that a chemical attack was carried out in Douma on April 7 and "there is no plausible scenario other than that of an attack by Syrian armed forces as part of a wider offensive" in the area. 

It added that Russia has "undeniably" provided active military support for Damascus and "provided constant political cover to the Syrian regime over the employment of chemical weapons."

At an emergency meeting Saturday of the U.N. Security Council, Russian ambassador Vassily Nebenzia said Russian experts on the ground in Douma found no evidence of a chemical attack. He said the alleged attack had been "staged" by foreign intelligence services.

He demanded a vote by the 15-member Security Council on a resolution condemning the "aggression" against Syria by the U.S., Britain and France, but the measure was voted down.

Only three countries — Russia, China and Bolivia —voted in favor of the resolution. Eight countries voted against and three abstained. A resolution needs at least 9 “yes” votes to be approved.

U.N. Secretary-general Antonio Gutteres condemned the use of chemical weapons but sought to reduce tension.

"I urge all member states to show restraint in these dangerous circumstances and to avoid any acts that could escalate matters and worsen the suffering of the Syrian people," he said.

Nikki Haley, U.S. ambassador to the U.N., said "the time for talk ended last night" with the allied attack on Syrian chemical weapons sites.

"The pictures of dead children were not fake news, they were the result of the Syrian regime's barbaric inhumanity," she said.

The U.S. envoy said the U.S. had tried numerous efforts to get Syria to give up its chemical weapons program and had no option but to act militarily.

"When our president draws a red line, our president enforces the red line," Haley said.

"We are prepared to sustain this pressure if the Syrian regime is foolish enough to test our will," she said, warning that in the event of another chemical attack by Syria, the U.S. is "locked and loaded."

While Russia and Syria sharply condemned the U.S., British and French attack, their initial response was verbal not military.

Russia’s U.S. embassy released a statement warning that the airstrikes will “not be left without consequences.” It said that “all responsibility” rests with Washington, London and Paris.

An international inspection team from the Organization for the Prohibition of Chemical Weapons planned to enter the city Saturday to investigate last week's chemical weapons attack.

Syria's President Bashar Assad announced that his country would respond to the allied attack but offered no details.

In Damascus immediately after the attack, hundreds of residents — many waving Syrian, Russian and Iranian flags — rushed to the landmark Omayyad square of the Syrian capital. Some clapped their hands and danced, other drove in convoys, honking their horns in defiance.

“We are your men, Bashar,” they shouted, according to the Associated Press.

“This military intervention is very important after what happened,” said Abu Thaa’r, an unemployed 32-year-old from Idleb in a phone interview. “Either these [chemical] weapons are internationally prohibited or not. The air strikes should have happened earlier.”

He was optimistic that American might and US allies would help his country.

“The bombings will change the situation in Syria, especially in terms of limiting the role of Russia,” said Thaa’r. “The bombing maybe will also help in getting rid of the Assad regime and find a solution for the crisis by having new order that we the Syrian people want.”

“Everybody was expecting the strike,” said Faten Bahda, 27, a Sunni Muslim woman who lives in Dummar, a western district of Damascus where many Shiite militia from Iraq and Iran have brought their families as they fight rebels. 
 
Her family had already packed their bags. Now, they were trying to flee Syria because they expected President Bashar Al-Assad to use the airstrikes as a pretext for crackdown on Sunni Mulims like her family.
 
"The regime will use this as a chance to continue sectarian policies against Sunni civilians,” she said in a  phone interview. “Things are going to get worse and we are going to try and get in a car today to get to Beirut.”

The U.S. has about 2,000 troops on the ground in Syria as advisers to a makeshift group of anti-Islamic State fighters known as the Syrian Democratic Forces. They are in eastern Syria, far from Damascus. A U.S.-led coalition has been conducting airstrikes in Syria since September 2014 as part of a largely successful effort to break the militants' grip on both Syria and Iraq.

Contributing: Jacob Wirtschafter in Cairo; Gilgamesh Nabeel in Turkey; The Associated Press.

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