The moves in Asia came on the back of U.S. and European stocks falling overnight after President Donald Trump signed a memorandum that would implement tariffs on up to $60 billion in imports from China.
The tariffs largely focus on technology sector goods and were intended to penalize China for, according to the Trump administration, stealing intellectual property.
Trump had signed off on tariffs on steel and aluminum imports earlier this month, although several countries were exempt. Markets are worried that subsequent retaliatory actions from U.S. trading partners could result in a trade war.
In response, China on Friday proposed a list of 128 U.S. products as potential retaliation targets, according to a government statement.
The fact that Trump's "announcement was a proposal rather than an action on trade indicates this may be used as a negotiating tactic," Diana Mousina, senior economist at Sydney-based AMP Capital said in a morning note.
Still, others worried that the tougher talk on trade could potentially lead to more significant consequences.
"[T]he real risk is that this escalates into tit-for-tat trade wars," Vishnu Varathan, head of economics and strategy at Mizuho Bank, said in a note.
The dollar extended losses against the safe-haven yen on the back of trade-related fears, with the greenback trading at 104.76 at 12:06 p.m. HK/SIN. The yen touched its highest levels in 16-months earlier.
The dollar index, which tracks the dollar against a basket of six currencies, traded at 89.613.
— CNBC's Kevin Breuninger, Kayla Tausche and Nyshka Chandran contributed to this report.