US stocks weakened into the close on Wednesday and Australian stocks were down 0.5 per cent in the first hour of trading.
The declines came after the US Federal Reserve delivered a widely-expected rate hike while keeping its median forecast for the Fed funds target at 2.1 per cent for 2018.
However, it lifted its median forecast for 2019 to 2.9 per cent, from 2.7 per cent, and for 2020 it raised the median forecast to 3.4 per cent from 3.1 per cent.
Matthew Sherwood, head of investment strategy at Perpetual Investments, said: "I think that investors are getting a bit worried about how much hiking the Fed is planning to do."
The Fed on showed on Wednesday that they will clamp down on the US economy in time, he said.
Broadly, the US rate hike is another chapter in the story that markets are getting past the easy stage of the cycle, that the sweet spot of improving economic growth and dovish central banks is coming to an end, Mr Sherwood added.
"The easy gains and the glory days of this cycle are over," he said. "I suspect that the second half of the year is going to be bumpy. At best it will be a grind, at worst we will see more volatilty."