Liverpool boss Jurgen Klopp has admitted he is wary of Tottenham following their win over Manchester United in midweek.
"We have a few nice options where we could make changes or not. The last game was good," he said.
"Spurs were sharp and awake the whole game v Man United. You don't often keep United as far away from your goal as Spurs did in that game.
"It's the most similar game to playing City. When you play one of the best teams in the world you have to put in your best performance."
Liverpool and Tottenham have both gone strong.
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Liverpool opt to deploy their formidable front three of Mohamed Salah, Sadio Mane and Roberto Firmino.
The trio caused Manchester City all sorts of problems when the two teams clashed last month.
Tottenham, meanwhile, start Harry Kane.
The England international is the top scorer in the Premier League with 21 goals so far.
Read below for full teams.
Liverpool team: Karius, Alexander-Arnold, Van Dijk, Lovren, Robertson, Can, Henderson, Milner, Mane, Salah, Firmino
Subs: Mignolet, Wijnaldum, Moreno, Oxlade-Chamberlain, Ings, Solanke, Matip
Tottenham team: Lloris, Trippier, Sanchez, Vertonghen, Davies, Dier, Dembele, Eriksen, Dele, Son, Kane
Subs: Vorm, Kurier, Wanyama, Winks, Sissoko, Lamela, Llorente
