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Brighton meet West Ham on the back of a 1-1 draw at fellow strugglers Southampton on Wednesday.
West Ham drew 1-1 at home to Crystal Palace 24 hours earlier and Seagulls boss Chris Hughton is expecting another tight encounter at the Amex.
Hughton said: "At home would probably be the disappointment that we haven't picked up more wins.
"We have just seen Swansea pick up two outstanding results at home [against Liverpool and Arsenal) that most people probably wouldn't have expected.
"Would they have been able to do that away from home? It would have been a lot harder.
"Home form will play the biggest part of this end of the season."
West Ham manager David Moyes is down to the bare bones.
He said: "We're getting the players back little by little and the games thin out a bit over the coming weeks, when the games go Saturday to Saturday, so that should help us as well."
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