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Tennis Channel recaps Day 4 at the Australian Open, where No. 3 seed Garbine Muguruza and No. 9 Johanna Konta lost as temperatures cracked triple digits. USA TODAY Sports

MELBOURNE — Reigning Wimbledon champion Garbine Muguruza was upset by 88th-ranked Hsieh Su-Wei of Tapiei 7-6 (7-1), 6-4 in the second round of the Australian Open on a Thursday.

The third-seeded Muguruza is the highest seed to fall in the women’s draw. The next highest to depart the Australian Open was fifth-seeded Venus Williams, who lost on the opening day of the competition.

Players were performing in intense heat conditions as temperatures soared to over 100 degrees.

"She's definitely a very tricky opponent — today she played well," said Muguruza, acknowledging that the heat was bothersome, but it wasn't the hottest conditions she'd experienced in Australia. "I could have done things better, but at the end, she deserves to win."

Muguruza, who ranked as high as No. 1 last season, finished 2017 with a year-end best finish of No. 2. Currently ranked third, Muguruza had an opportunity to return to the No. 1 ranking this fortnight but had to reach the final.

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Her 2017 success, which also included the Cincinnati title, resulted in her being named the 2017 ITF World Champion.

No Spanish woman has ever won the Australian Open title, although Conchita Martinez (1998) and Arantxa Sanchez Vicario (1994-95) reached the final during their careers.

Wimbledon was the second career Grand Slam trophy for Muguruza, who won her first at the 2016 French Open.

Muguruza made too many unforced errors against Hsieh — 43 — which created issues for her throughout the 1-hour, 59-minute match.

The Spaniard has had a frustrating start to the 2018 season. In Brisbane, where she received a first-round bye, she retired during her second-round match with cramps midway through the third set. In Sydney, a thigh injury prevented her from playing her quarterfinal match.

The 32-year-old Hsieh's best Australian Open result came in 2008 when as a qualifier she journeyed to the round-of-16 before losing to Justine Henin.

Follow Sandra Harwitt on Twitter @TennisGrapevine. Contributing: Associated Press.

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Australian Open: Best from the early rounds

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Day 4: Novak Djokovic chases down a backhand return against Gael Monfils during the second round.  Lukas Coch, EPA-EFE

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Gael Monfils plays a serve to Novak Djokovic during the second round.  Vincent Thian, AP

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Day 4: Angelique Kerber serves to Donna Vekic during the second round.  Julian Smith, EPA-EFE

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Day 4: Angelique Kerber celebrates after beating Donna Vekic in the second round.  Mark Kolbe, Getty Images

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Day 4: Maria Sharapova plays a backhand return against Anastasija Sevastova during the second round.  Cameron Spencer, Getty Images

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Day 4: Maria Sharapova celebrates after beating Anastasija Sevastova in the second round.  Dean Lewins, EPA-EFE

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Day 4: American Bernarda Pera is overcome after knocking off ninth-seeded Johanna Konta in the second round.  Mast Irham, EPA-EFE

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Day 4: Bernarda Pera plays a forehand return against Johanna Konta during the second round.  Andy Brownbill, AP

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Day 4: Bernarda Pera celebrates her second-round upset of Johanna Konta.  Andy Brownbill, AP

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Day 4: Lesia Tsurenko uses ice towels to keep cool as temperatures surpassed 100 degrees.  William West, AFP/Getty Images

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Day 4: Tim Smyczek laments a missed shot during his second-round loss against Albert Ramos-Vinolas.  William West, AFP/Getty Images

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Day 4: Karolina Pliskova chases down a forehand return against Beatriz Haddad Maia during the second round.  Peter Parks, AFP/Getty Images

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Day 4: Garbine Muguruza lines up a serve against Hsieh Su-wei during the second round.  Lukas Coch, EPA-EFE

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Day 4: Caroline Garcia celebrates after a tough three-set victory over Marketa Vondrousova in the second round.  Dita Alangkara, AP

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Day 4: A couple of fans stay "hydrated" on a hot afternoon.  Narendra Shrestha, EPA-EFE

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Day 4: Guillermo Garcia-Lopez reaches for a backhand return against Tomas Berdych during the second round.  Mast Irham, EPA-EFE

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Day 4: The promotions staff stays cool.  Narendra Shrestha, EPA-EFE

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Day 4: Garbine Muguruza tries to cool down between sets against Hsieh Su-Wei during the second round.  Saeed Khan, AFP/Getty Images

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Day 4: Marketa Vondrousova plays a forehand return to Caroline Garcia during the second round.  Dita Alangkara, AP

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Day 4: Barbora Strycova celebrates after defeating Lara Arruabarrena in the second round.  Ng Han Guan, AP

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Caroline Wozniacki reacts after defeating Jana Fett during their second round match.  Andy Brownbill, AP

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Caroline Wozniacki celebrates her win against Jana Fett during the second round.  DEAN LEWINS, EPA-EFE

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Caroline Wozniacki in action against Jana Fett during the second round.  TRACEY NEARMY, EPA-EFE

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Rafael Nadal reacts against Leonardo Mayer during the second round.  TRACEY NEARMY, EPA-EFE

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Rafael Nadal makes a backhand return to Leonardo Mayer during their second round match.  Andy Brownbill, AP

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Jo-Wilfried Tsonga celebrates his win over Denis Shapovalov during their second round match.  Dita Alangkara, AP

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Jo-Wilfried Tsonga celebrates after defeating Denis Shapovalov during their second round match.  Vincent Thian, AP

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Pablo Carreno Busta makes a backhand return to Simon Gilles during their second round match.  Dita Alangkara, AP

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Marin Cilic celebrates a point win over Joao Sousa during their second round match.  Vincent Thian, AP

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Marin Cilic in action against Joao Sousa during the second round.  JULIAN SMITH, EPA-EFE

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Elina Svitolina celebrates her win against Katerina Siniakova during the second round.  DEAN LEWINS, EPA-EFE

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Elina Svitolina hits a return against Katerina Siniakova during their women's singles second round match on Day 3.  WILLIAM WEST, AFP/Getty Images

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Marta Kostyuk celebrates a point win over Olivia Rogowska during their second round match.  Dita Alangkara, AP

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Marta Kostyuk reaches for a forehand return to Olivia Rogowska during their second round match.  Dita Alangkara, AP

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Madison Keys celebrates her win over Wang Qiang during their first round match at the Australian Open.  Ng Han Guan, AP

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Madison Keys celebrates a point win over Wang Qiang during their first round match at the Australian Open.  Ng Han Guan, AP

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Madison Keys in action during her first round match against Wang Qiang at the Australian Open.  MAST IRHAM, EPA-EFE

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Simona Halep celebrates after defeating Destanee Aiava during their first round match at the Australian Open.  Vincent Thian, AP

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Destanee Aiava serves against Simona Halep during on Day 2 of the Australian Open.  LUKAS COCH, EPA-EFE

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Simona Halep grabs her leg before receiving medical treatment in her match against Destanee Aiava on Day 2 of the Australian Open.  JOE CASTRO, EPA-EFE

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Novak Djokovic celebrates beating Donald Young in their men's singles first round match on Day 2 of the Australian Open.  GREG WOOD, AFP/Getty Images

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Novak Djokovic makes a backhand return to Donald Young during their first round match at the Australian Open.  Dita Alangkara, AP

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Stan Wawrinka celebrates his win over Ricardas Berankis during their first round match at the Australian Open.  Andy Brownbill, AP

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Alexander Zverev makes a backhand return to Thomas Fabbiano during their first round match at the Australian Open.  Dita Alangkara, AP

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Maria Sharapova celebrates her victory against Tatjana Maria during their women's singles first round match on Day 2 of the Australian Open.  GREG WOOD, AFP/Getty Images

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Stanislas Wawrinka hits a return against Ricardas Berankis during their men's singles first round match on Day 2 of the Australian Open.  WILLIAM WEST, AFP/Getty Images

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Angelique Kerber runs to make a forehand return to Anna-Lena Friedsam during their first round match at the Australian Open.  Andy Brownbill, AP

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Day 1: Belinda Bencic celebrates her upset victory over Venus Williams in the first round.  Cameron Spencer, Getty Images

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Day 1: Belinda Bencic serves to Venus Williams during the first round.  Joe Castro, EPA-EFE

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Day 1: Venus Williams tries to chase down a forehand return against Belinda Bencic during the first round.  Vincent Thian, AP

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Day 1: Zhang Shuai celebrates her first-round upset of Sloane Stephens.  Dita Alangkara, AP

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Day 1: Zhang Shuai runs down a backhand return against Sloane Stephens during the first round.  William West, AFP/Getty Images

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Day 1: Sloane Stephens laments a missed shot during her first-round loss to Zhang Shuai.  Dita Alangkara, AP

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Day 1: CoCo Vandeweghe lines up a serve against Timea Babos during the first round.  Andy Brownbill, AP

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Day 1: Venus Williams runs down a forehand return against Belinda Bencic during the first round.  Vincent Thian, AP

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Day 1: Jason Kubler laments a missed shot against Pablo Carreno Busta during the first round.  Lukas Coch, EPA-EFE

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Day 1: Jelena Ostapenko celebrates a point over Francesca Schiavone during the first round.  Vincent Thian, AP

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Day 1: Sofia Kenin reaches for a backhand return against Julia Goerges during the first round.  Andy Brownbill, AP

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Day 1: Timea Babos plays a serve to Coco Vandeweghe during the first round.  Saeed Khan, AFP/Getty Images

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Day 1: Denis Istomin plays a backhand return to Pierre-Hugues Herbert during the first round.  Peter Parks, AFP/Getty Images

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Day 1: Ekaterina Makarova plays a forehand return against Irina-Camelia Begu during the first round.  Lukas Coch, EPA-EFE

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Day 1: Pablo Cuevas plays a forehand return against Mikhail Youzhny during the first round.  Mark Cristino, EPA-EFE

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