There was a time when PD-1/L1 immunotherapy treatments could do no wrong, blasting through indication after indication. However, the limits of the therapies are beginning to be found with a series of surprise failures across a number of indications.
The first major one was Opdivo’s failure as first-line treatment in lung cancer, after this ice-breaker, of sorts, there have been a number of subsequent failures that have called into question how far the treatments can be pushed.
Original Article: Keytruda falls hard at gastric cancer hurdle
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