Don't judge a cell by its cover: heterogeneity within early lymphoid progenitors

B-cell differentiation is one of the most recognized examples of the progressive lineage commitment that is distinctive for stem cell systems. However, the characteristics of the stage just before a cell becomes restricted to the B-cell lineage are less understood. Using single-cell RNA sequencing technology, Rolink and colleagues are able to define the cellular heterogeneity at this step and challenge our understanding of developmental trajectories in early B-lymphoid development (Alberti-Servera et al, 2017).

Original Article: Don't judge a cell by its cover: heterogeneity within early lymphoid progenitors

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