Researchmoz added Most up-to-date research on "Cancer Supportive Care
Drug Development Pipeline Review, 2017" to its huge collection of
research reports.
This report provides an overview of the Cancer Supportive Care pipeline
landscape. The report provides comprehensive information on the
therapeutics under development and key players involved in therapeutic
development for cancer anorexia-cachexia syndrome, bone metastasis and
cancer pain, and features dormant and discontinued projects.
Anorexia is defined as the loss of the desire to eat. Progressive
wasting is common in many types of cancer and is one of the most
important factors leading to early death in cancer patients. Advanced
cancer undergo a wasting syndrome associated with cancer
anorexia-cachexia and asthenia, which is associated with weakness,
fatigue, and a poor quality of life. Bone metastasis occurs when cancer
cells spread from their original site to a bone. Signs and symptoms of
bone metastasis include bone pain, broken bones, urinary incontinence,
bowel incontinence and weakness in the legs. Cancer pain can be defined
as a complex sensation that reflects both damage to the body and the
body's response to the damage. Pain may arise due to tumor compressing
or infiltrating tissue, from treatments and diagnostic procedures, or
from skin, nerve and other changes caused by either the body's immune
response or hormones released by the tumor.
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The size of these pipelines ranges 24 products in cancer
anorexia-cachexia syndrome to 52 in cancer pain. The majority of
products in cancer anorexia-cachexia syndrome target the growth hormone
secretagogue receptor type 1, although there are a range of other
molecular targets in development. Within bone metastasis, the most
common molecular targets are the tumor necrosis factor ligand
superfamily member 11, and the hepatocyte growth factor receptor, along
with a range of others. Finally, within cancer pain, neurotransmitters
such as the mu type opioid receptor, and a range of ion channels, are
the most common type of target, reflecting the pain treatment landscape
in general.
Scope
- Which companies are the most active within each pipeline?
- Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
- To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
- What are the most important R&D milestones and data publications to have happened in this disease area?
Reasons to buy
- Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
- Assess the products in development in granular detail, with an
up-to-date overview of each individual pipeline program in each
indication, and a comprehensive picture of recent updates and milestones
for each
- Analyze the companies, institutions and universities currently
operating in the pipeline, and the products being fielded by each of
these
- Understand the composition of the pipeline in terms of molecule type,
molecular target, mechanism of action and route of administration
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Table of Contents
1 Table of Contents 4
1.1 List of Tables 5
1.2 List of Figures 7
2 Introduction 8
2.1 Cancer Supportive Care Report Coverage 8
2.2 Cancer Anorexia-Cachexia Syndrome Overview 8
2.3 Bone Metastasis Overview 8
2.4 Cancer Pain Overview 8
3 Therapeutics Development 9
3.1 Cancer Anorexia-Cachexia Syndrome 9
3.2 Bone Metastasis 15
3.3 Cancer Pain 21
4 Therapeutics Assessment 27
4.1 Cancer Anorexia-Cachexia Syndrome 27
4.2 Bone Metastasis 34
4.3 Cancer Pain 41
5 Companies Involved in Therapeutics Development 49
5.1 Cancer Anorexia-Cachexia Syndrome 49
5.2 Bone Metastasis 54
5.3 Cancer Pain 63
6 Dormant Projects 80
6.1 Cancer Anorexia-Cachexia Syndrome 80
6.2 Bone Metastasis 82
6.3 Cancer Pain 84
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