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Jason Wolf explains how the Titans have failed to get a win in Indianapolis in more than a decade. Autumn Allison/USA TODAY NETWORK-Tennessee

Who has the edge between the Titans (6-4) and Colts (3-7) on Sunday (noon CT, Fox) at Lucas Oil Stadium?

Offense - Titans

Quarterback Marcus Mariota still was limited by a hamstring injury when he returned to lead the Titans to a victory against the Colts earlier this season. He’s healthy this time around and will be motivated to get the Titans back on the winning track after throwing a career-high four interceptions in his last outing against the Steelers. Colts quarterback Jacoby Brissett, playing in place of the injured Andrew Luck, leads one of the more feeble offenses in the NFL.

Defense - Titans

The Colts are allowing an average of 28 points per game, the most in the league. They're ranked 30th in pass defense and total defense. The Titans rate among the strongest teams in the NFL against the rush and should be able to limit plodding veteran running back Frank Gore, rendering the Colts’ offense one-dimensional.

Tennessee Titans vs. Indianapolis Colts
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Titans linebacker Brian Orakpo (98) celebrates the
Titans linebacker Brian Orakpo (98) celebrates the team's win over the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans linebacker Wesley Woodyard (59) celebrates with
Titans linebacker Wesley Woodyard (59) celebrates with running back Derrick Henry (22) after Henry's touchdown late in the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans quarterback Marcus Mariota (8) signs autographs
Titans quarterback Marcus Mariota (8) signs autographs after the team's 36-22 win over the Colts att Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans defensive end David King (95) signs his jersey
Titans defensive end David King (95) signs his jersey before trading with Colts defensive end Margus Hunt (92) after the Titans victory at Nissan Stadium in Nashville, Tenn., Monday, Oct. 16, 2017.  Andrew Nelles / Tennessean.com
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Titans quarterback Marcus Mariota (8) signs autographs
Titans quarterback Marcus Mariota (8) signs autographs after the team's 36-22 win over the Colts att Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans defensive end David King (95) gets help removing
Titans defensive end David King (95) gets help removing his jersey from Colts defensive end Margus Hunt (92) before they swapped jerseys after the Titans victory at Nissan Stadium in Nashville, Tenn., Monday, Oct. 16, 2017.  Andrew Nelles / Tennessean.com
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Titans quarterback Marcus Mariota (8) chats with Colts
Titans quarterback Marcus Mariota (8) chats with Colts quarterback Jacoby Brissett (7) after the Titans' 36-22 win at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans head coach Mike Mularkey and Colts head coach
Titans head coach Mike Mularkey and Colts head coach Chuck Pagano shake hands after the Titans win at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans quarterback Marcus Mariota (8) shakes hands
Titans quarterback Marcus Mariota (8) shakes hands with injured Colts quarterback Andrew Luck (12) after the Titans' win at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans players cheer linebacker Wesley Woodyard (59)
Titans players cheer linebacker Wesley Woodyard (59) after he forced Colts quarterback Jacoby Brissett (7) out of bounds, turning the ball over on downs, and preserving the Titans' win, late in the fourth quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans linebacker Wesley Woodyard (59) pushes Colts
Titans linebacker Wesley Woodyard (59) pushes Colts quarterback Jacoby Brissett (7) out of bounds during the fourth quarter to turn the ball over on downs and preserve the Titans' win at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans linebacker Wesley Woodyard (59) pushes Colts
Titans linebacker Wesley Woodyard (59) pushes Colts quarterback Jacoby Brissett (7) out of bounds during the fourth quarter to turn the ball over on downs and preserve the Titans' win at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans linebacker Wesley Woodyard (59) pushes Colts
Titans linebacker Wesley Woodyard (59) pushes Colts quarterback Jacoby Brissett (7) out of bounds during the fourth quarter to turn the ball over on downs and preserve the Titans' win at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans linebacker Wesley Woodyard (59) pushes Colts
Titans linebacker Wesley Woodyard (59) pushes Colts quarterback Jacoby Brissett (7) out of bounds during the fourth quarter to turn the ball over on downs and preserve the Titans' win at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans defensive tackle Jurrell Casey (99) celebrates
Titans defensive tackle Jurrell Casey (99) celebrates late in the fourth quarter of the Titans' win over the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans linebacker Wesley Woodyard (59) stops Colts
Titans linebacker Wesley Woodyard (59) stops Colts wide receiver Donte Moncrief (10) during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans head coach Mike Mularkey watches the team late
Titans head coach Mike Mularkey watches the team late in the fourth quarter of a 36-22 win over the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans running back Derrick Henry (22) gains yards
Titans running back Derrick Henry (22) gains yards late in the fourth quarter of the team's win over the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Colts tight end Jack Doyle (84) pushes Titans safety
Colts tight end Jack Doyle (84) pushes Titans safety Kevin Byard (31) out of bounds during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans wide receiver Taywan Taylor (13) scores a touchdown
Titans wide receiver Taywan Taylor (13) scores a touchdown during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans wide receiver Taywan Taylor (13) celebrates
Titans wide receiver Taywan Taylor (13) celebrates his touchdown with wide receiver Rishard Matthews (18) during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.co
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Titans wide receiver Taywan Taylor (13) is wide open
Titans wide receiver Taywan Taylor (13) is wide open on the catch for a touchdown during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans head coach Mike Mularkey discusses a call with
Titans head coach Mike Mularkey discusses a call with down judge Jerod Phillips (6) during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans running back DeMarco Murray (29) scores the
Titans running back DeMarco Murray (29) scores the team's first touchdown in the game during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans quarterback Marcus Mariota (8) reaches out for
Titans quarterback Marcus Mariota (8) reaches out for running back DeMarco Murray (29) after Murray's touchdown during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans quarterback Marcus Mariota (8) celebrates with
Titans quarterback Marcus Mariota (8) celebrates with Titans running back DeMarco Murray (29) after Murray's touchdown during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans linebacker Wesley Woodyard (59) celebrates his
Titans linebacker Wesley Woodyard (59) celebrates his fumble recovery during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Colts tight end Jack Doyle (84) loses the ball defended
Colts tight end Jack Doyle (84) loses the ball defended by Titans linebacker Jayon Brown (55) and recovered by linebacker Wesley Woodyard (59) during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans wide receiver Rishard Matthews (18) goes up
Titans wide receiver Rishard Matthews (18) goes up over Colts safety Malik Hooker (29) during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans place kicker Ryan Succop (4) kicks his fifth
Titans place kicker Ryan Succop (4) kicks his fifth field goal in the game during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans tight end Delanie Walker (82) can't hang onto
Titans tight end Delanie Walker (82) can't hang onto a pass during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans running back DeMarco Murray (29) gets stopped
Titans running back DeMarco Murray (29) gets stopped by Colts linebacker Antonio Morrison (44) and linebacker Jonathan Bostic (57) during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans wide receiver Eric Decker (87) stretches for
Titans wide receiver Eric Decker (87) stretches for extra yards defended by Colts cornerback Nate Hairston (27) during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans tight end Delanie Walker (82) gains yards during
Titans tight end Delanie Walker (82) gains yards during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans tight end Delanie Walker (82) gains yards during
Titans tight end Delanie Walker (82) gains yards during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Colts linebacker John Simon (51) reacts to his touchdown
Colts linebacker John Simon (51) reacts to his touchdown and interception during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Colts linebacker John Simon (51) runs back his interception
Colts linebacker John Simon (51) runs back his interception for a touchdown during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans quarterback Marcus Mariota (8) drops back to
Titans quarterback Marcus Mariota (8) drops back to pass during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Colts linebacker John Simon (51) runs back his interception
Colts linebacker John Simon (51) runs back his interception for a touchdown during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Colts linebacker John Simon (51) reacts to his touchdown
Colts linebacker John Simon (51) reacts to his touchdown and interception during the second half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans cornerback Adoree' Jackson (25) gets stopped
Titans cornerback Adoree' Jackson (25) gets stopped on a runback on the six-yard line as Colts linebacker Barkevious Mingo (52) gets upended during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans cornerback Adoree' Jackson (25) gets stopped
Titans cornerback Adoree' Jackson (25) gets stopped on the six-yard-line on a runback during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans running back Derrick Henry (22) gains yards
Titans running back Derrick Henry (22) gains yards during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans wide receiver Rishard Matthews (18) gets stopped
Titans wide receiver Rishard Matthews (18) gets stopped by Colts linebacker John Simon (51) during the firsthalf at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans quarterback Marcus Mariota (8) passes during
Titans quarterback Marcus Mariota (8) passes during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans running back Derrick Henry (22) gets stopped
Titans running back Derrick Henry (22) gets stopped by Colts linebacker Antonio Morrison (44) after a run during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans place kicker Ryan Succop (4) celebrates his
Titans place kicker Ryan Succop (4) celebrates his third field goal during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans cornerback Curtis Riley (35) can't stop Colts
Titans cornerback Curtis Riley (35) can't stop Colts tight end Jack Doyle (84) as he goes in for a touchdown during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Colts tight end Jack Doyle (84) pats Colts quarterback
Colts tight end Jack Doyle (84) pats Colts quarterback Jacoby Brissett (7) on the helmet after Doyle scored a touchdown during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Colts cornerback Pierre Desir (35) scores on Titans
Colts cornerback Pierre Desir (35) scores on Titans cornerback Curtis Riley (35) during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans linebacker Avery Williamson (54) and safety
Titans linebacker Avery Williamson (54) and safety Kevin Byard (31) stop Colts quarterback Jacoby Brissett (7) on a run during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Colts tight end Jack Doyle (84) celebrates his touchdown
Colts tight end Jack Doyle (84) celebrates his touchdown with teammates wide receiver Donte Moncrief (10) and offensive tackle Anthony Castonzo (74) during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans cheerleaders lead the fans during the second
Titans cheerleaders lead the fans during the second quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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A Titans fan cheers the team during the second quarter
A Titans fan cheers the team during the second quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans linebacker Wesley Woodyard (59) and linebacker
Titans linebacker Wesley Woodyard (59) and linebacker Avery Williamson (54) move in to tackle Colts running back Frank Gore (23) during the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Colts running back Marlon Mack (25) gains yard as Titans
Colts running back Marlon Mack (25) gains yard as Titans defensive end DaQuan Jones (90) misses a stop during the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans safety Kevin Byard (31) and cornerback Adoree'
Titans safety Kevin Byard (31) and cornerback Adoree' Jackson (25) stop Colts wide receiver Donte Moncrief (10) during the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Colts quarterback Jacoby Brissett (7) looks to hand
Colts quarterback Jacoby Brissett (7) looks to hand off to to Colts running back Frank Gore (23) during the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Colts running back Marlon Mack (25) moves the ball
Colts running back Marlon Mack (25) moves the ball during the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Colts punter Rigoberto Sanchez (2) and place kicker
Colts punter Rigoberto Sanchez (2) and place kicker Adam Vinatieri (4) slap hands after a field goal during the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans fans watch the first quarter at Nissan Stadium
Titans fans watch the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans quarterback Marcus Mariota (8) takes a snap
Titans quarterback Marcus Mariota (8) takes a snap during the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans wide receiver Eric Decker (87) makes a catch
Titans wide receiver Eric Decker (87) makes a catch during the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans place kicker Ryan Succop (4) kicks his second
Titans place kicker Ryan Succop (4) kicks his second field goal of the night during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans long snapper Beau Brinkley (48) congratulates
Titans long snapper Beau Brinkley (48) congratulates place kicker Ryan Succop (4) after his field goal during the first half at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Colts cornerback Rashaan Melvin (30) hangs onto Titans
Colts cornerback Rashaan Melvin (30) hangs onto Titans running back Derrick Henry (22) early in the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans quarterback Marcus Mariota (8) throws a pass
Titans quarterback Marcus Mariota (8) throws a pass during the first quarter against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans place kicker Ryan Succop (4) kicks the first
Titans place kicker Ryan Succop (4) kicks the first field goal during the first quarter at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans running back DeMarco Murray (29) gains yards
Titans running back DeMarco Murray (29) gains yards early in the first quarter Monday, Oct. 16, 2017, at Nissan Stadium in Nashville.  Andrew Nelles / tennessean.com
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T-Rac leads cheers with the Titans cheerleaders before
T-Rac leads cheers with the Titans cheerleaders before the start of the game at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans linebacker Erik Walden (93) slaps hands with
Titans linebacker Erik Walden (93) slaps hands with fans in the tunnel at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans safety Da'Norris Searcy (21) points heavenward
Titans safety Da'Norris Searcy (21) points heavenward before the game at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans cornerback Adoree' Jackson (25) hugs his mom,
Titans cornerback Adoree' Jackson (25) hugs his mom, a breast cancer survivor, during pregame ceremonies at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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The Titans line up fore the National Anthem before
The Titans line up fore the National Anthem before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Country star Trace Adkins sings the National Anthem
Country star Trace Adkins sings the National Anthem before the start of the Titans game at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans defensive tackle Jurrell Casey (99) and linebacker
Titans defensive tackle Jurrell Casey (99) and linebacker Wesley Woodyard (59) during the national anthem at Nissan Stadium on Monday, Oct. 16, 2017, in Nashville  George Walker IV / Tennessean.com
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Titans wide receiver Rishard Matthews (18) stayed in
Titans wide receiver Rishard Matthews (18) stayed in the tunnel and entered the field after the National Anthem at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  Andrew Nelles / tennessean.com
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Titans quarterback Marcus Mariota (8) warms up before
Titans quarterback Marcus Mariota (8) warms up before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans defensive tackle Jurrell Casey (99) leads his
Titans defensive tackle Jurrell Casey (99) leads his team as they huddle before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans quarterbacks Marcus Mariota (8) and Matt Cassel
Titans quarterbacks Marcus Mariota (8) and Matt Cassel (16) warm up before the start of the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Nashville Mayor Megan Barry meets with Titans owner
Nashville Mayor Megan Barry meets with Titans owner Amy Adams Strunk before the game at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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The Titans huddle before the start of the game against
The Titans huddle before the start of the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans quarterback Marcus Mariota (8) hands off to
Titans quarterback Marcus Mariota (8) hands off to running back DeMarco Murray (29) during warmups before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans linebacker Wesley Woodyard (59) leads the team
Titans linebacker Wesley Woodyard (59) leads the team in huddle before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans quarterback Marcus Mariota (8) warms up before
Titans quarterback Marcus Mariota (8) warms up before the start of the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans defensive end DaQuan Jones (90) walks on the
Titans defensive end DaQuan Jones (90) walks on the field before the game at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans tight end Delanie Walker (82) warms up before
Titans tight end Delanie Walker (82) warms up before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans safety Johnathan Cyprien (37) warms up before
Titans safety Johnathan Cyprien (37) warms up before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans tight end Jonnu Smith (81) warms before the
Titans tight end Jonnu Smith (81) warms before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Monday Night Football sportscasters Randy Moss, right,
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Monday Night Football sportscasters Randy Moss, right, and Steve Young chat before the Titans's game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / The Tennessean
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Titans fan Drew Hicks shows his allegiance before the
Titans fan Drew Hicks shows his allegiance before the start of the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans cornerback Tye Smith (33) warms up before the
Titans cornerback Tye Smith (33) warms up before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans safety Johnathan Cyprien (37) talks with NFL
Titans safety Johnathan Cyprien (37) talks with NFL agent Drew Rosenhaus before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans place kicker Ryan Succop (4) warms up before
Titans place kicker Ryan Succop (4) warms up before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans cornerback Logan Ryan (26) makes a catch during
Titans cornerback Logan Ryan (26) makes a catch during warmups before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans cornerback Adoree' Jackson (25) makes a catch
Titans cornerback Adoree' Jackson (25) makes a catch before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans wide receiver Taywan Taylor (13) warms up before
Titans wide receiver Taywan Taylor (13) warms up before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Titans wide receiver Rishard Matthews (18) makes a
Titans wide receiver Rishard Matthews (18) makes a catch during warmups before the game against the Colts at Nissan Stadium Monday, Oct. 16, 2017 in Nashville, Tenn.  George Walker IV / tennessean.com
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Oskar Ward, 7, has his face painted in the fan area
Oskar Ward, 7, has his face painted in the fan area before a game between the Titans and the Colts at Nissan Stadium in Nashville, Tenn., Monday, Oct. 16, 2017.  Andrew Nelles / Tennessean.com
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Chris Friesen, who is on vacation from Canada, throws
Chris Friesen, who is on vacation from Canada, throws a football in the fan area before a game between the Titans and the Colts at Nissan Stadium in Nashville, Tenn., Monday, Oct. 16, 2017.  Andrew Nelles / Tennessean.com
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Fans dance to music in the fan area before a game between
Fans dance to music in the fan area before a game between the Titans and the Colts at Nissan Stadium in Nashville, Tenn., Monday, Oct. 16, 2017.  Andrew Nelles / Tennessean.com
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Donna Mauer, of Orlando, Fla., rides a zipline in the
Donna Mauer, of Orlando, Fla., rides a zipline in the fan area before a game between the Titans and the Colts at Nissan Stadium in Nashville, Tenn., Monday, Oct. 16, 2017.  Andrew Nelles / Tennessean.com
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Fans listen to music in the fan area before a game
Fans listen to music in the fan area before a game between the Titans and the Colts at Nissan Stadium in Nashville, Tenn., Monday, Oct. 16, 2017.  Andrew Nelles / Tennessean.com
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    Special teams - Colts

    Colts kicker Adam Vinatieri ranks among the most accurate in the league, having hit 18 of 19 field-goal attempts. The Titans have missed a field goal in each of the past two weeks. Ryan Succop missed against the Bengals to end his NFL record streak of 56 consecutive field goals from inside 50 yards. The Titans had another field-goal attempt blocked against the Steelers. Titans punter Brett Kern leads the NFL in average and net punting yards. Tennessee’s kickoff coverage unit is giving up the second-most yards in the league.

    Coaching - Colts

    Chuck Pagano owns a 10-1 record against the Titans and was undefeated until Tennessee’s victory earlier this season on “Monday Night Football.” He is 2-4 against teams coached by Mike Mularkey. Pagano guided the Colts to a 49-31 regular-season record in his first five seasons in Indianapolis, including three 11-win campaigns.

    Intangibles - Titans

    The Colts are coming off a bye week and have won nine consecutive games against the Titans in Indianapolis. The Titans’ last victory in Indy came in 2007 at the RCA Dome. They never have won at Lucas Oil Stadium. But the Titans remain in the playoff picture, unlike the Colts, and did manage to snap an 11-game losing streak to their AFC South rival earlier this season in Nashville. The Titans are angry after losing a mistake-filled, nationally televised game to the Steelers, 40-17, on “Thursday Night Football.” This is a critical juncture in their season.

    Predictions

    Jason Wolf

    Titans 28, Colts 24: Mariota finds great success against the Colts’ 30th-ranked pass defense, leading the Titans to their first victory in Indianapolis in a decade and keeping them within striking distance of the AFC South title.

    Joe Rexrode

    Titans 27, Colts 17: It's time for the Titans to stop messing around and win a game they should win in convincing nature. Here's a perfect opportunity. The defense will get after Brissett, and the offense will find ample room to make plays against that Colts defense.

    Reach Jason Wolf at jwolf@tennessean.com and follow him on Twitter @JasonWolf and on Instagram and Snapchat at TitansBeat.