Research aims to develop diagnostic tools for pathogen detection
ReadCoor, Inc., a company reinventing omics and pathology with its panomic spatial sequencing platform, today announced a collaboration with The Joint Pathology Center (JPC), the premier pathology reference center for the United States government. The project will focus on the development of diagnostics tools for determining the pathogenic cause of mortality using Fluorescent in situ Sequencing (FISSEQ).
The JPC, a Department of Defense laboratory, specializes in pathology consultation, education and research. The center also houses the nation’s oldest tissue repository. ReadCoor will utilize its novel sequencing platform, FISSEQ, to identify the pathogenic cause of mortality from RNA, DNA and proteins localized in a variety of inflamed tissue samples from the center’s repository.
FISSEQ’s ability to sequence samples without disrupting sample structure provides researchers and pathologists with unprecedented spatial data, and the ability to generate reads without advance knowledge of sequences of interest. This powerful platform can detect mutated pathogens, identify contamination, separate pathogens of mortality (e.g. Ebola) from benign pathogens (e.g. rhinovirus), and correlate pathogen location with inflammation. FISSEQ provides the most complete clinical atlas of molecular, DNA, RNA, and proteins of the host and pathogen for diagnosis, prognosis, and treatment.
About Fluorescent in situ Sequencing (FISSEQ)
FISSEQ
is a spatial sequencing technology that reads and visualizes the
three-dimensional coordinates of molecules of intact tissue, a
capability that stands to revolutionize panomics and pathology. FISSEQ
was developed in the Church Lab at Harvard University and the Wyss
Institute for Biologically Inspired Engineering, and first published in Science
in 2014 (Highly
multiplexed three-dimensional subcellular transcriptome sequencing in
situ). The platform has broad application in the areas of drug
development, diagnostics, and machine learning.
About ReadCoor, Inc.
ReadCoor is leading the next generation
of omics by delivering the first panomic spatial sequencing platform to
the global audience of researchers, clinicians, pharma and diagnostics
companies, and ultimately patients. It is accomplishing this with
Fluorescent in situ Sequencing (FISSEQ), a fundamental new
technology, which simultaneously integrates high-throughput sequencing,
and three-dimensional morphometric analysis. This uniquely powerful
platform is expected to revolutionize the next phase in understanding
the panomic landscape and introduce vast new opportunities for important
and meaningful clinical insight.
View source version on businesswire.com: http://www.businesswire.com/news/home/20171109005101/en/
ReadCoor, Inc.
Christine Lafontant, 617-453-2659
christine.lafontant@readcoor.com
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