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Two independent modes of chromatin organization revealed by cohesin removal
19:53 EDT 1 Nov 2017 | Nature Publishing
Imaging and chromosome conformation capture studies have revealed several layers of chromosome organization, including segregation into megabase-sized active and inactive compartments, and partitioning into sub-megabase domains (TADs). It remains unclear, however, how these layers of organization form, interact with one another and influence genome function.
Original Article: Two independent modes of chromatin organization revealed by cohesin removal
