Mutant gene found to fuel cancer-promoting effects of inflammation

(University of California - San Diego) A study by UC San Diego biologists uncovered a new mechanism linking a human gene's function to chronic inflammation. Through large-scale genomic analyses, the researchers discovered that 'mutant p53' amplifies the impact of inflammation, leading to increases in the invasive behavior of cancer. Thus, rather than fighting tumor growth, mutant forms of p53 appear to be tapping into the body's immune response system to fuel pro-inflammatory responses that increase cancer growth.

Original Article: Mutant gene found to fuel cancer-promoting effects of inflammation

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